diff --git a/lang/python/host-pip-requirements/cffi.txt b/lang/python/host-pip-requirements/cffi.txt
index 867d004752..94ef13b55a 100644
--- a/lang/python/host-pip-requirements/cffi.txt
+++ b/lang/python/host-pip-requirements/cffi.txt
@@ -1,2 +1,2 @@
 cffi==1.15.0 --hash=sha256:920f0d66a896c2d99f0adbb391f990a84091179542c205fa53ce5787aff87954
-pycparser==2.20 --hash=sha256:2d475327684562c3a96cc71adf7dc8c4f0565175cf86b6d7a404ff4c771f15f0
+pycparser==2.21 --hash=sha256:e644fdec12f7872f86c58ff790da456218b10f863970249516d60a5eaca77206
diff --git a/lang/python/python-pycparser/Makefile b/lang/python/python-pycparser/Makefile
index 29d81c9cb7..c0da351577 100644
--- a/lang/python/python-pycparser/Makefile
+++ b/lang/python/python-pycparser/Makefile
@@ -8,11 +8,11 @@
 include $(TOPDIR)/rules.mk
 
 PKG_NAME:=python-pycparser
-PKG_VERSION:=2.20
-PKG_RELEASE:=5
+PKG_VERSION:=2.21
+PKG_RELEASE:=1
 
 PYPI_NAME:=pycparser
-PKG_HASH:=2d475327684562c3a96cc71adf7dc8c4f0565175cf86b6d7a404ff4c771f15f0
+PKG_HASH:=e644fdec12f7872f86c58ff790da456218b10f863970249516d60a5eaca77206
 
 PKG_LICENSE:=BSD-3-Clause
 PKG_LICENSE_FILES:=LICENSE
diff --git a/lang/python/python-pycparser/patches/001-use-external-ply.patch b/lang/python/python-pycparser/patches/001-use-external-ply.patch
index 23c43d2803..b6f2eac955 100644
--- a/lang/python/python-pycparser/patches/001-use-external-ply.patch
+++ b/lang/python/python-pycparser/patches/001-use-external-ply.patch
@@ -1,8 +1,8 @@
 --- a/pycparser/c_lexer.py
 +++ b/pycparser/c_lexer.py
-@@ -9,8 +9,8 @@
+@@ -8,8 +8,8 @@
+ #------------------------------------------------------------------------------
  import re
- import sys
  
 -from .ply import lex
 -from .ply.lex import TOKEN
@@ -13,10 +13,10 @@
  class CLexer(object):
 --- a/pycparser/c_parser.py
 +++ b/pycparser/c_parser.py
-@@ -8,7 +8,7 @@
+@@ -6,7 +6,7 @@
+ # Eli Bendersky [https://eli.thegreenplace.net/]
+ # License: BSD
  #------------------------------------------------------------------------------
- import re
- 
 -from .ply import yacc
 +from ply import yacc
  
@@ -24,8 +24,8 @@
  from .c_lexer import CLexer
 --- a/setup.py
 +++ b/setup.py
-@@ -60,7 +60,7 @@ setup(
-         'Programming Language :: Python :: 3.6',
+@@ -64,7 +64,7 @@ setup(
+         'Programming Language :: Python :: 3.10',
      ],
      python_requires=">=2.7, !=3.0.*, !=3.1.*, !=3.2.*, !=3.3.*",
 -    packages=['pycparser', 'pycparser.ply'],